As the most common malignant pediatric brain tumour, medulloblastoma (MB) remains one of the leading causes of childhood cancer mortality with median survival dependent on molecular classification.
Team Medulloblastoma: (from left to right) Ashley Adile, David Bakhshinyan (alumnus), Sheila Singh, Michelle Kameda-Smith (alumnus), Chitra Venugopal, Stefan Custers (not pictured), William Gwynne (not pictured)
Glioblastoma (GBM) is the most aggressive adult brain cancer, with a 15-month median survivorship, attributed to the highly aggressive, treatment-refractory brain tumour initiating cell population.
Team Glioblastoma: (from left to right) Nazanin Tatari, Deepak Upreti, Neil Savage, Emily Ford (alumnus), Parvez Vora (alumnus), Maleeha Qazi (alumnus), Sheila Singh, Chitra Venugopal, Mathieu Seyfrid, Sabra Salim, Dillon McKenna, Chirayu Chokshi, William Maich (not pictured)
Primary lung, breast and skin tumour often migrate to the brain, seeding brain metastases (BM), which hold a median survival time of only months in affected patients, despite current clinical modalities.
Team Brain Metastasis: (from left to right) Blessing Bassey-Archibong, Sheila Singh, Agata Kielishek, Chitra Venugopal, Nikoo Aghaei, Fred Lam (not pictured)
Catch a glimpse behind the scenes to how our research discoveries are made. In the laboratory, we work with tissue culture from animal models and patient samples, measuring outcomes and analyzing results using gold-standard molecular biology techniques in state-of-the-art facilities at the McMaster Stem Cell and Cancer Research Institute.
Dr. Sheila Singh | Pediatric Neurosurgeon, McMaster Children’s Hospital | Principal Investigator, McMaster Cancer Research Centre
Michael G. DeGroote Centre for Learning and Discovery, Room 5027 | McMaster University | 1280 Main Street West | Hamilton, Ontario L8S4K1
Dr. Sheila Singh | Pediatric Neurosurgeon, McMaster Children’s Hospital | Principal Investigator, McMaster Cancer Research Centre | Michael G. DeGroote Centre for Learning and Discovery, Room 5027 | McMaster University | 1280 Main Street West | Hamilton, Ontario L8S4K1